1,2,3-triazoles (including hydrogenated)

.beta.-PHENYL-.beta.-AZOLYL-NITROETHANES OF THE FORMULA ##SPC1## In which R.sup.1, r.sup.2 and R.sup.3 each individually is hydrogen, lower alkyl optionally substituted by fluorine or chlorine, halogen, nitrile, thiocyano, nitro or alkoxycarbonyl with up to 6 carbon atoms in the alkoxy radical, and R.sup.4...     

A process for inhibiting plant growth comprising contacting a plant or its growth area with an effective amount of certain para-halophenyl substituted triazolines. A series of novel mesoionic para-halophenyl substituted triazolines. A novel process for preparing 3-phenyl-4-oxo-1,2,3-triazoline by contacting...     

A process for inhibiting plant growth comprising contacting a plant or its growth area with an effective amount of certain para-halophenyl substituted triazolines. A series of novel mesoionic para-halophenyl substituted triazolines. A novel process for preparing 3-phenyl-4-oxo-1,2,3-triazoline by contacting...     

The present invention provides novel compounds of the formula: ##SPC1## In which R.sub.1 signifies hydrogen, fluorine or chlorine atom, a carboxylic or sulphonic acid group or an amide or ester thereof, a cyano group or an alkylsulphonyl or arylsulphonyl group, R.sub.2 signifies a hydrogen, fluorine...     

Novel N-benzyltriazoles of the formula ##SPC1## In which Triazolyl is 1,2,4 or 1,2,3 triazolyl which may be substituted; X is halogen, trifluoromethyl, lower alkyl, lower alkoxy, lower alkylthio, aryl, nitro, cyano or (alkylated) amino; m is 0, 1 or 2; A is optionally substituted phenyl, pyridyl, alkyl...     

Compounds of the class of 1-heteroarylsulphonyl-2-imino-imidazolidines which are substituted in the 3-position by an aliphatic or cycloaliphatic hydrocarbon radical, especially a cycloalkyl radical, and their pharmaceutically acceptable acid addition salts have valuable pharmacological properties. In...     

A 5-hydroxy-1,2,3-triazole-4-carboxamide nucleoside, related to the C-nucleoside pyrazomycin, is facilely synthesized by condensation of acyl-blocked ribofuranose with trimethylsilylated 5-hydroxy-1,2,3-triazole-4-carboxamide or, alternatively, by cycloaddition of suitably blocked .beta.-D-ribofuranosyl...     

Certain phenyl- and (substituted)-phenyl-1,2,3-triazole-alkanoic and -alkenoic acids exhibit antiinflammatory or antipyretic activity.

Certain phenyl- and (substituted)-phenyl-1,2,3-triazole-alkanoic and -alkenoic acids exhibit antiinflammatory or antipyretic activity.

Triazolyl-O,N-acetals of the formula ##EQU1## in which R.sup.1 and R.sup.4 each independently is alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, aryl, or aralkyl, R.sup.2 and R.sup.3 each independently is hydrogen or one of the radicals mentioned under R.sup.1, and A is a 1,2,4-triazolyl-(1), 1,2,4-triazolyl-(4)...     

Sulfonic acid esters of the formula R.sub.1 -- SO.sub.2 -- O -- R.sub.2 wherein R.sub.1 represents alkyl or alkenyl, and R.sub.2 represents an unsubstituted or substituted heteroaromatic five-membered ring having three hetero atoms, processes for their manufacture, and their use in pest control.

The compounds of this invention are cephalosporins having various acyl substituents at the 7-position and a substituted triazolyl thiomethyl group at the 3-position of the cephem nucleus and intermediates for the preparation thereof. The 7-acylated compounds have antibacterial activity.

New azolylamidines of the formula ##SPC1## Wherein n is an integer from 0 to 5, R.sup.1 is halogen, alkyl, alkoxy, alkylthio, haloalkoxy, haloalkylthio, halophenoxy or haloalkyl; R.sup.2 and R.sup.3, independently of one another, are each hydrogen, alkyl, alkoxyalkyl, cycloalkyl, alkoxy or alkoxycarbonylalkyl,...     

Compounds of the formula (I) ##STR1## in which R is hydrogen, or lower alkyl, which may be substituted by phenyl, hydroxy, lower carbalkoxy or cyano, X is hydrogen, chlorine, methyl, methoxy, cyano or lower carbalkoxy, n is 1 to 3, and A is an aromatic carboxylic group or an aromatic hetero-cyclic 5-...     

This invention relates to certain novel .alpha.-amino- or .alpha.-formyl-.alpha.-(p-acyloxyphenyl)acetamidocephalosporanic acids which are useful as antibacterial agents.

Anhydrides and esters of alkyl or cycloalkyl tetracarboxylic acids and polyvinyl chloride plastic compositions containing said esters as plasticizers.

A novel triazole compound of the formula: ##STR1## The compound is particularly effective as pre-emergency herbicide. Dosages of 2.5 Kg/Ha to 10 Kg/Ha are recommended.

Stilbene compounds of the formula ##STR1## wherein Q denotes the 1,3,4-oxadiazol-2,5-ylene or 1,2,4-oxadiazol-3,5-ylene radical and Q.sub.1 denotes one of the radicals ##STR2## and the rings A, B, C, D and E can each contain 1 to 3 non-chromophoric substituents.

Disclosed are optical brightening agents, such agents being 2-(2')-benzimidazoyl-furans substituted in the 5-position of the furan ring by a 1-aryl-pyrazolyl-3, -4 or -5 radical, by a pyrazolyl-1 radical or by a 2-aryl-v-triazolyl-4 radical, such compounds being in free base, acid addition or quaternary...     

This invention relates to aminals of aromatic hydroxy-aldehydes and to a process for the production thereof. The compounds can be used in the production of dyes.

Styrene compounds of the formula ##STR1## wherein Q denotes one of the ring systems of the formulae ##STR2## wherein M represents oxygen or sulphur, Z represents hydrogen, lower alkyl or phenyl and n represents the number 1 or 2 and the rings A and B can each contain 1 to 3 non-chromophoric substituents.

Stilbene derivatives having at least one further phenyl substituent in the para-position to a benzene ring in the stilbene are optical brighteners particularly suitable for incorporation on spinning masses.

The compounds are ethylene derivatives which are inhibitors of histamine activity, in particular, inhibitors of H-2 histamine receptors. A compound of this invention is 1-nitro-2-methylamino-2-[2-((4-methyl-5-imidazolyl)methylthio)-ethylamino] ethylene.

Substituted thioindoles and their sulfoxide and sulfone derivatives, useful as cardiac rate lowering agents and for other pharmacological properties, and precursors therefor.

1,2,3-triazoles and 1,2,4-triazoles having an N-substituted acylamino substituent are prepared by alkylating N-unsubstituted acylamino triazoles or acylating N-substituted amino triazoles. The N-substituted acylamino triazoles are useful as anti-allergy drugs. Pharmaceutical formulations containing acylamino...     

1,2,3-Triazole-4(5)-thiol is prepared by treating 1-benzyl-1,2,3-triazole with a strong base, treating the resulting anion with sulfur, removing the benzyl group by reductive means, and acidifying the resulting thiolate with strong acid.

An improved and novel process is provided for the reduction of isocyanate groups in organic compounds to formamide groups by catalytic hydrogenation with a noble metal catalyst. The process allows preparation of formamides in consistently high yields from all types of isocyanates.

The compounds are substituted thioalkyl-,aminoalkyl- and oxyalkyl-guanidines which are inhibitors of histamine activity.

Novel 4-(v-triazolyl)-styryl compounds of the formula ##STR1## wherein n is 0, 1 or 2, R represents a hydrogen atom or an unsubstituted or substituted alkyl, alkenyl, aralkyl, alkanoyl or aroyl group and Q represents an unsubstituted or substituted 5-membered heterocyclic ring or, if n is 1 or 2, also...     

The compounds are ethylene derivatives which are inhibitors of histamine activity, in particular, inhibitors of H-2 histamine receptors. A compound of this invention is 1-nitro-2-methylamino-2-[2-((4-methyl-5-imidazolyl)methylthio)ethylamino]e thylene.

Disclosed are compounds of formula I, ##STR1## in which X signifies hydrogen, C.sub.1-4 alkyl, cyano, --COOM, --COOR.sub.1, --CONR.sub.2 R.sub.3, --SO.sub.2 NR.sub.2 R.sub.3, --SO.sub.2 R.sub.1, --SOR.sub.1, --SO.sub.3 R.sub.1 or --SO.sub.3 M, Y signifies hydrogen, C.sub.1-4 alkyl, cyano, --COOM, --COOR.sub.1,...     

This invention relates to new di-triazolylstyrene derivatives, useful as optical brighteners for organic polymeric materials, especially when applied to or incorporated in synthetic fibres.

Novel stilbene compounds of the formula ##STR1## in which A is the radical ##STR2## in which R.sub.1 is hydrogen or chlorine and R.sub.2 is hydrogen or alkyl, Z is hydrogen, chlorine or phenyl and R.sub.3 is hydrogen, alkyl or chlorine, as well as their use in a process for optically brightening organic...     

Pyrazoline compounds of the formula (I): ##STR1## in which each of B.sup.1 to B.sup.5 is hydrogen or C.sub.1 to C.sub.4 alkyl; R.sup.1 is hydrogen, alkyl or hydroxy; R.sup.2, R.sup.3, R.sup.5, R.sup.6 and R.sup.7 independently of one another are hydrogen, chloro, bromo, fluoro, methyl, ethyl, methoxy...     

Substituted 1-aralkyl-1H-v-triazoles are prepared from a suitable 1-aralkyl-1H-v-triazole by a process comprising an alkylation step and dependent on the product desired suitably followed by an oxidation step and decarboxylation step.

The subject matter are triazolyl-stilbenes of the formula ##STR1## wherein R.sub.1 represents an optionally substituted styryl, biphenylyl or naphthyl radical, R.sub.2 represents hydrogen, halogen, or an alkyl or phenyl radical and R.sub.3 represents nitrile, carboxyl or carboxylic acid ester, as well...     

Novel 2,4-Bis-(stilben-4'-yl)-v-triazoles of the formula ##STR1## wherein the rings A, B, C, D and E can contain certain nonchromophoric substituents, methods for their preparation as well as their use as optical brighteners are disclosed.

Compounds of the formula (I): ##STR1## and pharmaceutically acceptable salts thereof wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 which may be the same of different, represent hydrogen, halogen, nitro, lower alkyl, and lower alkoxy, or any adjacent two of R.sub.1 to R.sub.4 taken together represent...     

The compounds are sulphoxides of heterocyclicthioalkylthioureas, ureas and guanidines which are useful to produce inhibition of histamine H-2 receptors.

Novel heterocyclic anthracycline compounds having antitumor activity against murine P388 leukemia in mice.

There is presented triazolobenzazepines of the formula ##STR1## wherein R.sub.1 is hydrogen or lower alkyl and X and Y are hydrogen or halogen and the pharmaceutically acceptable salts thereof. Also disclosed are novel processes and intermediates leading to the triazolobenzazepines. The triazolobenzazepines...     

There is presented triazolobenzazepines of the formula ##STR1## wherein R.sub.1 is hydrogen or lower alkyl and X and Y are hydrogen or halogen and the pharmaceutically acceptable salts thereof. Also disclosed are novel processes and intermediates leading to the triazolobenzazepines. The triazolobenzazepines...     

There is presented triazolobenzazepines of the formula ##STR1## wherein R.sub.1 is hydrogen or lower alkyl and X and Y are hydrogen or halogen and the pharmaceutically acceptable salts thereof. Also disclosed are novel processes and intermediates leading to the triazolobenzazepines. The triazolobenzazepines...     

Dyestuffs of the formula ##STR1## wherein R.sup.1, R.sup.2, R denote H, alkyl, alkenyl, cycloalkyl, aralkyl etc. R.sup.3, R.sup.4 denote H, alkyl, aralkyl, aryl, alkoxy, halogen, CN, COOH, alkoxycarbonyl, alkylsulfonyl, arylsulfonyl etc. Z denotes O, S or --N(R)--, p and q denote 0 or 1, but not simultaneously...     

New 4-nitro-2-trichloromethylphenylsulfenamides having a fungicidal and bactericidal action, processes for their manufacture, fungicides containing these compounds as active ingredients, and a process for combating fungi with these compounds.

Compounds of the formula ##STR1## in which R.sub.1 denotes aryl, alkyl, aralkyl, styryl or alkoxy, R.sub.2 denotes hydrogen, cyano, carboxyl or alkoxycarbonyl, inter alia, R.sub.3, R.sub.4, R.sub.6 and R.sub.7 denote hydrogen, alkyl, alkoxy or halogen, R.sub.5 denotes hydrogen, alkyl or aryl, R.sub.8...     

A process is disclosed for selectively making trans-cyclohexane-1,4-diisocyanate, trans-cyclohexane-1,4-diamine, a trans-cyclohexane-1,4-diurethane, a trans-cyclohexane-1,4-diurea and trans-cyclohexane-1,4-disulphonyl urea by reacting ammonia with a mixture of cis and trans cyclohexane-1,4-dicarboxylic...     

A novel fuel composition contains ethanol or gasohol plus, as a corrosion inhibitor, a reaction product of aminotriazole and polyisobutenyl succinic acid anhydride.

A novel fuel composition contains ethanol or gasohol plus, as a corrosion inhibitor, a reaction product of an aminotriazole, isatoic anhydride and an N-alkyl propylene diamine.

The compounds are C.sub.2 -C.sub.8 straight chain alkanes terminally substituted symmetrically or unsymmetrically, by N-(N'-substituted guanidino), N-(N',N"-disubstituted guanidino), N-(N'-substituted thioureido), N-(nitromethylene amidino) or S-(N-substituted isothioureido) groups. Two compounds of...     

The invention relates to stilbene derivatives which are used as optical brightening agents, particularly as anionic brightening agents for polyamide and cellulosic substrates. These stilbene derivatives have the formula I ##STR1## in which both X's are the same and are CR.sub.5 or N, where R.sub.5 is...     

The compounds are ethylene derivatives which are inhibitors of histamine activity, in particular, inhibitors of H-2 histamine receptors. A compound of this invention is 1-nitro-2-methylamino-2-[2-((4-methyl-5-imidazolyl)methylthio)ethylamino]e thylene.

A process for making 5-mercapto-1,2,3-triazoles of the formula ##STR1## wherein R.sub.1 is hydrogen or a C.sub.1 -C.sub.4 -alkyl which may also be substituted, the said process comprising (1) as a first step reacting a solution of 1,2,3-thiadiazole-5-carbohydroxamic acid derivative of the formula ##STR2##...     

A process for the preparation of an .alpha.-ketocarboxylic acid N-tert.-butylamide of the formula R--CO--CO--NH--C(CH.sub.3).sub.3 in which R is an aliphatic radical with up to 8 carbon atoms, a cycloalkyl radical with 3 to 6 carbon atoms, a phenyl or naphthyl radical or a heterocyclic radical, comprising...     

A process for protecting cultivated plants against aggressive agricultural chemicals is described in which oxime derivatives of the formula ##STR1## are used as antidotes. Either the cultivated area for the cultivated plants or the cultivated plants themselves or parts of the plant (seeds, tubers, stem...     

2-(Azol-1-yl)-aldoxime-carbamates of the formula ##STR1## wherein R.sup.1 and R.sup.2 each independently is alkyl or together form an alkylene bridge, R.sup.3 is hydrogen or alkyl, R.sup.4 is hydrogen, alkyl, alkenyl, alkynyl, halogenoalkyl, halogenoalkenyl, alkoxyalkyl or alkylthioalkyl, and Az is azolyl,...     

N-Sulphenylated oxime-carbamates of the formula ##STR1## in which R is alkyl or optionally substituted cycloalkyl, aryl or aralkyl, R.sup.1 is an optionally substituted N-containing heterocyclic radical or an alkyl or cycloalkyl radical substituted by an optionally substituted N-containing heterocyclic...     

.alpha.-Ketocarboxylic acid N-acylamides of the formula R.sup.1 --CO--CO--NH--CO--R.sup.2 in which R.sup.1 is an optionally substituted aliphatic radical with up to 12 carbon atoms, an optionally substituted cycloalkyl radical with 3 to 10 carbon atoms, an optionally substituted heterocyclic radical,...     

Histamine H.sub.2 -antagonists of the formula ##STR1## wherein p is 1 or 2; R.sup.1 is hydroxy, amino, substituted amino or a 5- to 9-membered fully saturated nitrogen-containing heterocyclic ring attached via its nitrogen atom; m is an integer of from 0 to 2; n is an integer of from 2 to 4; Z is sulfur,...     

Phenoxy-aminopropanol derivatives of the formula ##STR1## wherein R is lower alkyl, X is oxygen or sulfur, n is the integer zero or 1, Y is methylene, ethylene or propylene or, when n is zero, Y can also be a group of the formula --CH.dbd.CH--C*H.sub.2 -- (a) , wherein the double-bond is trans and the...     

A compound of the formula (I): ##STR1## wherein R.sub.1 is hydrogen or C.sub.1-6 alkyl; R.sub.2, R.sub.3 and R.sub.4 are the same or different and are chosen from hydrogen, hydroxyl, halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy and C.sub.1-4 alkanoyl; G is H or OH; and m and n are independently 1 to 3;...     

Compounds of the formula (I): ##STR1## and pharmaceutically acceptable salts thereof, wherein R.sub.1 is hydrogen or C.sub.1-6 alkyl, and R.sub.2 is hydroxy, C.sub.1-4 alkylsulphonyloxy or p-toluenesulphonyloxy are useful for the prophylaxis and treatment of diseases due to allergic response in mammals....     

Acyl cyanides of the formula ##STR1## in which R represents an optionally substituted alkyl group having 1 to 8 carbon atoms, an optionally substituted cycloalkyl group having 3 to 12 carbon atoms or an optionally substituted aryl group, or an optionally substituted 5-membered or 6-membered heterocyclic...     

Novel thioesters effective as acylating agents for amines or hydrazines, especially effective as active esters in synthesis of cephalosporin compounds are disclosed. The novel thioester of the present invention can be prepared by reacting a thiol or a derivative thereof with an acetic acid derivative...     

Carboxylic acid anhydrides of the general formula R--CO--O--CO--R' (I) in which R and R' are identical or different and represent an optionally substituted alkyl group having 1 to 18 carbon atoms, an optionally substituted cycloalkyl group having 3 to 12 carbon atoms or an optionally substituted aryl...     

R.sub.2 is hydrogen, halogen, amino, nitro, alkoxy of 1 to 3 carbon atoms, --COOR.sub.6, 3-methyl or 4-methyl; R.sub.4 and R.sub.5 are each alkyl of 1 to 4 carbon atoms or, together with each other and the nitrogen atom to which they are attached, piperidino, pyrrolidino or morpholino; R.sub.6 is alkyl...     

Useful novel ketene O,O-acetals of the formula I ##STR1## where R.sup.1 is a tertiary alkyl radical of 4 to 6 carbon atoms or unsubstituted or halogen-substituted phenyl, R.sup.2 is hydrogen and R.sup.3 and R.sup.4 independently of one another are each phenyl which is unsubstituted or substituted by...     

Novel amine oxide compounds of the formula ##STR1## in which m is the integer 1 or 2, A is a through-conjugated radical of a fluorescent brightener system, which radical contains unsubstituted or non-chromophorically substituted aromatic carbocyclic and/or heterocyclic rings, X is a direct bond between...     

Alkylene(cycloalkylene)-bis-heterocyclyl-biguanides of the formula ##STR1## in which A and B each independently is a nitrogen-containing heterocyclic radical which is linked via a nitrogen atom, R is an optionally alkyl-substituted cycloalkylene radical, or an alkylene radical which is optionally substituted...     

New fused imidazole compounds of the formula: ##STR1## wherein A is lower alkylene, R.sup.1 is hydrogen, lower alkyl, lower alkoxy or halogen, R.sup.2 is hydrogen, lower alkyl, cyclo(lower)alkyl, pyridyl, ar(lower)alkyl which may be substituted with halogen, or aryl which may be substituted with lower...     

Phenoxy-aminopropanol derivatives of the formula ##STR1## wherein R is lower alkyl, X is oxygen or sulfur, n is the integer zero or 1, Y is methylene, ethylene or propylene or, when n is zero, Y can also be a group of the formula ##STR2## wherein the double-bond is trans and the carbon atom marked with...     

Certain 1-heterocyclicthio-1-cyclopropanecarbonitriles have been found to reduce herbicidal injury of certain food crops due to the application thereto of herbicides that kill or control weeds that impede the yield of crops.

Novel antibacterially-active esters of antibiotic nodusmicin. Activity is demonstrated against Staphylococcus aureus, Streptococcus pyogenes, and Sarcina lutea. Thus, these esters can be used in various known environments, using well-known procedures, to eradicate or control susceptible microbes.

Novel 5-amino or substituted amino 1,2,3-triazoles are disclosed as having anticoccidial activity. The compounds are useful for controlling coccidiosis when administered in minor quantities to animals, in particular to poultry, usually in admixture with animal sustenance.

New and valuable 2-halo-N-(azole-1-yl-methyl)-substituted acetanilides and having a good herbicidal action, and methods of controlling the growth of unwanted plants with these compounds.

A compound having the structural formula ##STR1## wherein X is hydrogen or bromine; Y is bromine, phenyl, C.sub.1 -C.sub.4 alkyl or C.sub.4 -C.sub.6 cycloalkyl; R.sup.1 and R.sup.2 independently are C.sub.1 -C.sub.6 alkyl or R.sup.1 and R.sup.2 together form a ring with the nitrogen to which they are...     

Combating fungi with novel 1-azolyl-substituted oxime ethers of the formula ##STR1## in which R is alkyl, alkoxyalkyl, alkenyl, alkinyl or cycloalkyl; or aralkyl, phenoxyalkyl or phenyl optionally substituted in the aromatic part, R.sup.1 is alkyl, alkenyl, alkinyl, or optionally substituted aralkyl...     

This invention provides a method of inhibiting aromatase and treating estrogen-dependent diseases in mammals by administering certain azole derivatives. Certain azole derivatives and their pharmaceutical formulations are also provided.

Anticonvulsant compositions comprise as the active ingredient a compound selected from the group consisting of those of the formulae: ##STR1## wherein R.sub.1 is phenyl, 4-pyridyl, 3-pyridyl, or 2-pyridyl, and R.sub.2 is hydrogen, m- or p-methyl, p-methoxy, m- or p-chloro, m- or p-bromo, m- or p-fluoro,...     

Antineoplastic compounds of the formula, IIa, ##STR1## wherein: Y is hydrogen or lower alkyl; and Z is a lower alkoxy substituted quinolinylamino radical, a cyano substituted pyrazolylamino radical or a mono- or di-lower alkyl substituted thiazolamino radical, or a nitrogen-containing heterocyclic radical,...     

Anticonvulsant compositions comprise as the active ingredient a compound selected from the group consisting of those of the formulae: ##STR1## wherein R.sub.1 is o-chlorophenyl, o-nitrophenyl, 2,4- or 2,6-dichlorophenyl, 4-pyridyl, 3-pyridyl, 2-pyridyl, or 2-quinolyl, and R.sub.2 is hydrogen, m- or p-trifluoromethyl,...     

A silver halide photographic light-sensitive material is described, comprising at least one light-sensitive silver halide emulsion layer on a support, wherein the emulsion in said light-sensitive silver halide emulsion layer comprises a silver iodobromide emulsion containing 3 mol % or more of iodide,...     

Disclosed are aryl(aryloxy or arylthio) azolomethanes, their preparation and their pesticidal and plant growth regulation uses.

This invention provides certain azole derivatives and their pharmaceutical formulations. Also provided is a method of inhibiting aromatase and treating or preventing estrogen-dependent diseases in mammals by administering the azole derivatives.

Phenoxy-aminopropanol derivatives of the formula ##STR1## wherein R is lower alkyl, X is oxygen or sulfur, n is the integer zero or 1, Y is methylene, ethylene or propylene or, when n is zero, Y can also be a group of the formula --CH.dbd.CH--C*H.sub.2 --, (a) wherein the double-bond is trans and the...     

The invention refers to substituted 6-(thien-2-yl)-3(2H)-pyridazinones of Formula I ##STR1##

Insecticidal and fungicidal compounds of the formula (I): ##STR1## wherein R.sup.1, X, Y, and Z are as defined in the specification and R.sup.2 is a 1H-azol-1-yl group containing 2 or 3 nitrogen atoms are disclosed.

The present invention relates to milbemycin derivatives of the formula I ##STR1## wherein X is hydrogen or .beta.-halogen, R is methyl, ethyl, isopropyl or sec-butyl and Az is a 5 membered heterocyclic aromatic ring which contains 2-4 nitrogen atoms and is attached in the 1-position and which is unsubstituted...     

Disclosed are aryl(aryloxy or arylthio) azolomethanes, their preparation and their pesticidal and plant growth regulation uses.

Novel sebum synthesis inhibiting compositions comprising a sebum inhibiting effective amount of at least one compound selected from the group consisting of compounds of the formula ##STR1## wherein R is selected from the group consisting of hydrogen and acyl of an organic carboxylic acid free of additional...     

Novel 5-amino or substituted amino 1,2,3-triazoles are disclosed as having anticoccidial activity. The compounds are useful for controlling coccidiosis when administered in minor quantities to animals, in particular to poultry, usually in admixture with animal sustenance.

1-Alkylated diazolidinones are intermediates to bicyclic pyrazolidinone antimicrobial compounds. The instant compounds have the formula ##STR1## wherein R.sub.1, R.sub.2, and R.sub.3, have the meanings as defined in the specification.

1-(Alkylated)-2-(acylated)diazolidinones are intermediates to bicyclic pyrazolidinone antimicrobial compounds. The instant compounds have the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, and R.sub.4 are as defined in the specification.

Novel methods for treatment of neoplastic disease states in animals, which methods comprise administering a therapeutically effective amount of a compound of the formula IIIa, ##STR1## wherein: Y is hydrogen or lower alkyl; and Z is an hydroxy substitited 1-pyrrolidinyl radical, or a lower alkyl substituted...     

Disclosed are additives which are useful as dispersants in lubricating oils, gasolines, marine crankcase oils and hydraulic oils. In particular, disclosed are multiply adducted alkenyl or alkyl succinimides which contain carbamate functionalities.

There are disclosed certain 1,2,3-triazole compounds with a substituted benzyl group at the 1-position, an amido group at the 4-position and a aminomethylene amino group at the 5-position. The compounds are prepared from the corresponding compound wherein the 5-position substituent is amino by treatment...     

Herbicidal mixtures comprising (1) a diphenyl ether of the formula: ##STR1## or a salt thereof, wherein R.sup.1 is, for example, alkyl; R.sup.2 is hydrogen, halogen or nitro; R.sup.3 is hydrogen, halogen, alkyl, trifluoromethyl or cyano; R.sup.4 is hydrogen, halogen or trifluoromethyl; R.sup.5 is hydrogen,...     

1-phenyl-lower alkyl-1H-1,2,3-triazole compounds of the formula ##STR1## in which Ph represents phenyl substituted by up to and including 3 substituents selected from lower alkyl, halogen and trifluoromethyl, alk represents lower alkylidene, and wherein either R.sub.1 represents hydrogen, lower alkyl,...     

Mitomycin derivatives having potent antitumor activity having the formula: ##STR1## wherein A is ON--or R.sub.4 N.dbd.N--[wherein R.sub.4 is selected from ##STR2## and optionally substituted heterocyclic groups (wherein R.sub.5 and R.sub.8 are each independently selected from hydrogen, lower alkyl and...     

Novel 5-amino or substituted amino 1,2,3-triazoles are disclosed as having anticoccidial activity. The compounds are useful for controlling coccidiosis when administered in minor quantities to animals, in particular to poultry, usually in admixture with animal sustenance.